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Nitrous oxide is an important occupational hazard for surgeons, dentists and nurses. As the fuel is minimally metabolised in individuals (having a charge of 0.
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Lengthy-phrase exposure to nitrous oxide may possibly induce vitamin B12 deficiency. This can cause severe neurotoxicity In case the consumer has preexisting vitamin B12 deficiency.[one hundred twenty] It inactivates the cobalamin kind of vitamin B12 by oxidation. Signs or symptoms of vitamin B12 deficiency, together with sensory neuropathy, myelopathy and encephalopathy, may happen within just days or even weeks of exposure to nitrous oxide anaesthesia in individuals with subclinical vitamin B12 deficiency.
Fifty percent nitrous oxide is often deemed for use by experienced non-Specialist initial support responders in prehospital settings, specified the relative simplicity and protection of administering 50% nitrous oxide being an analgesic. The speedy reversibility of its outcome would also avert it from precluding analysis.[97]
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